Why Aardvark Therapeutics (AARD) Paused Late-Stage ARD-101 Trials After Cardiac Findings

Aardvark Therapeutics, Inc. (NASDAQ:AARD) is 1 of the penny stocks with imaginable to emergence 1000 percent.

Aardvark Therapeutics said connected March 23, 2026, that it had voluntarily paused its Phase 3 HERO and open-label hold trials of ARD-101 successful Prader-Willi syndrome, arsenic good arsenic the ARD-201 obesity program, portion it works with the FDA connected adjacent steps. The institution said it expects to supply further guidance connected some programs successful the 2nd 4th of 2026.

The update was driven by cardiac findings from a abstracted steadfast unpaid study, not from anterior Prader-Willi syndrome trials. Aardvark said 2 of 8 participants successful a steadfast unpaid cohort dosed astatine 1,600 mg doubly regular without anterior dose escalation had QRS increases greater than 25% from baseline, portion different had an summation beneath that threshold. In a follow-on steadfast unpaid cohort dosed astatine 800 mg doubly regular for up to 1 week, 1 of 23 participants had a transient QRS summation of little than 25% from baseline, and different had an summation greater than 25%. The institution said these observations were reversible, were not reported arsenic superior adverse events, and were not accompanied by superior cardiac symptoms.

Aardvark said preliminary investigation showed a wide exposure-response relationship, with higher plasma concentrations associated with a higher hazard of QRS prolongation. It added that ARD-101 information were published successful Molecular Metabolism successful March. The institution ended 2025 with $110.0 cardinal successful cash, currency equivalents, and short-term investments, which it said should money operations into the 2nd 4th of 2027.

Aardvark Therapeutics, Inc. (NASDAQ:AARD) is simply a clinical-stage biopharmaceutical institution processing small-molecule therapies designed to suppress hunger successful Prader-Willi syndrome and metabolic diseases.

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