Merck Stock Looks Undervalued as KEYTRUDA Growth and Pipeline Offset Near-Term Headwinds

2 hours ago 1

Vandita Jadeja

Tue, May 5, 2026 astatine 12:17 PM CDT 4 min read

Quick Read

  • Merck (MRK) reported Q1 2026 gross of $16.29B, up 4.87% year-over-year and beating statement estimates, with KEYTRUDA income jumping 12% to $8.03B and WINREVAIR surging 88% to $525M contempt a $9.0B acquisition complaint from the Cidara deal.

  • Merck’s heavy Phase 3 oncology pipeline with near-term catalysts including WELIREG + KEYTRUDA adjuvant RCC determination successful June and 3 further PDUFA dates done October positions the institution for sustained maturation arsenic it manages done KEYTRUDA patent cliff risks and GARDASIL weakness successful China.

  • The expert who called NVIDIA successful 2010 conscionable named his apical 10 stocks and Merck wasn't 1 of them. Get them present FREE.

Merck (NYSE:MRK) delivered its 4th consecutive net beat, but shares slipped connected the net report. With acquisition charges clouding the quarter, present is wherever the banal heads next.

The 24/7 Wall St. Price Target for Merck Is $135.70

Our 24/7 Wall St. terms people for Merck is $135.70 implicit the adjacent 12 months, implying 24.29% upside from the existent $109.18. Our proposal is buy, with a assurance level of 90%. A antiaircraft healthcare profile, heavy Phase 3 pipeline, and banal trading good beneath its 52-week precocious make an charismatic setup for diligent investors.

An infographic titled 'MERCK 12-Month Price Prediction' showing 'Our Price Target'. It displays the existent   terms  of $109.18 arsenic  of May 1, 2026, with an arrow indicating a +24.29% upside to a people     terms  of $135.70, with a 'BUY' proposal   and 90% confidence. A conception  'HOW WE GOT THERE' shows barroom  charts for Trailing P/E-Based Price ($109.18), Forward P/E-Based Price ($125.43), Analyst Target Weight (0.3), and Weighted Base Price ($123.47). Another conception  'OUR ADJUSTMENTS' details proprietary 247Factor adjustments starting from Weighted Base of $123.47, with greenish  bars for affirmative  adjustments (Sector Momentum, Analyst Consensus, Volatility), a reddish  barroom  for antagonistic  accommodation  (Earnings Growth), starring  to a 247Factor of 1.099 and a Final Target of $135.70. The bottommost  portion  presents 'BULL CASE' scenarios (Pipeline Depth & Keytruda Growth +12%, WINREVAIR Acceleration +88%, Upcoming Phase 3 Data Readouts) with a people     of $141.16, and 'BEAR CASE' scenarios (Keytruda Patent Cliff Risk, China Sales Decline -47%, Failed Phase 3 Oncology Trials) with a people     of $114.09. The infographic concludes with 'THE BOTTOM LINE' stating a 'BUY' recommendation, a $135.70 Target, and +24.29% Upside, attributed to 24/7Wall St.

24/7 Wall St.

The expert who called NVIDIA successful 2010 conscionable named his apical 10 stocks and Merck wasn't 1 of them. Get them present FREE.

Metric

Value

Current Price

$109.18

24/7 Wall St. Price Target

$135.70

Upside

24.29%

Recommendation

BUY

Confidence Level

90%

A Quarter Dominated by KEYTRUDA and Acquisition Charges

Merck reported Q1 2026 gross of $16.29 billion, increasing 4.87% twelvemonth implicit twelvemonth and beating statement by 2.77%. Non-GAAP EPS of -$1.28 topped the -$1.47 estimate, a 13.15% beat. The header nonaccomplishment reflects a $9.0 cardinal Cidara acquisition charge, with operating show remaining intact.

KEYTRUDA generated $8.03 cardinal (up 12%), portion WINREVAIR jumped 88% to $525 million. Management raised full-year guidance to $65.80 cardinal to $67 cardinal successful gross and $5.04 to $5.16 successful non-GAAP EPS.

Despite the beat, shares slipped 1.6% connected the time and are down 9.24% implicit the past month, though up 32.8% implicit the past year.

The Case for $141 and Beyond

The bull thesis rests connected pipeline depth. The CEO highlighted "we are moving with velocity to alteration our portfolio to 1 with a diversified acceptable of maturation drivers crossed a wide acceptable of therapeutic areas... arsenic we participate a peculiarly robust play of Phase 3 information readouts."

Near-term catalysts see the June 19, 2026 WELIREG + KEYTRUDA adjuvant RCC PDUFA, the August 17, 2026 KEYTRUDA + Padcev MIBC decision, and the October 10, 2026 ifinatamab deruxtecan PDUFA.

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