The wearables industry has solved the comparatively casual stuff: measurement counting, slumber tracking, fittingness coaching. It has besides solved much analyzable things similar detecting atrial fibrillation and slumber apnea. While each of these biometrics are useful, the continuous tracking of humor sweetener successful a mode that’s noninvasive (meaning it doesn’t impact needles) has eluded the makers of fittingness tracking devices.
Diabetics request to show their humor sweetener perpetually to marque definite it doesn’t spell excessively precocious and harm their organs. This is particularly hard for aged radical and tiny children, since monitoring humor sweetener usually requires a pinprick humor trial oregon a continuous glucose show (CGM), which besides reaches nether the skin.
CGMs person besides go hugely fashionable among non-diabetics arsenic the popularity of GLP-1s has skyrocketed. Eating similar a diabetic—lots of macromolecule and fiber, minimal sweetener and carbs—is a large mode to suffer weight. Apple, among different companies, has spent years, and millions of dollars, trying to present a no-prick humor glucose show to the Apple Watch, but the diagnostic hasn’t arrived yet.
All this is to explicate wherefore I could scarcely judge that the PreEvnt Isaac was existent erstwhile I saw it present astatine CES 2026 successful Las Vegas. The Isaac is simply a tiny device, astir the size of a quarter. Instead of tracking humor glucose optically done the skin, it measures volatile integrated compounds successful your enactment to observe biomarkers similar acetone that tin beryllium correlated with rising humor glucose levels.
You mightiness not beryllium capable to deterioration it successful a astute ringing oregon watch, but a tiny instrumentality that you tin deterioration astir your cervix oregon support successful your container without having to retreat to the bath to prick your tegument is simply a immense measurement up successful prime of beingness for many, galore people.
Upcoming FDA Authorization

Photograph: Adrienne So
The Isaac is named aft the inventor’s grandson, who was diagnosed with benignant 1 diabetes astatine 2 years old. A 2-year-old doesn’t privation to get pricked constantly. Bud Wilcox realized that “acetone breath”—that sweet, fruity enactment that is simply a communal diabetic symptom—could beryllium utilized to cheque for humor sweetener events.
PreEvnt and Wilcox showcased the conception astatine CES 2025 (it didn’t look existent then, either). Later that year, the instrumentality entered progressive quality objective trials astatine Indiana University. The survey is comparing Isaac’s show with monitoring humor sweetener levels arsenic compared to accepted humor sweetener monitoring, starting with adolescents with benignant 1 diabetes and past expanding to adults with benignant 2 diabetes.
The trials are being conducted with an oculus toward regulatory reappraisal by the US Food and Drug Administration successful the upcoming year.











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