Maham Fatima
Wed, December 31, 2025 astatine 10:13 AM CST 2 min read
On December 2, TD Cowen initiated sum of C4 Therapeutics with a Buy standing but acceptable nary terms people connected the company’s shares. The steadfast highlighted that the institution distinguishes itself arsenic 1 of the fewer biotech firms to execute objective validation for some molecular glues and heterobifunctional degraders. TD Cowen specifically identifies cemsigwat/Cemsi arsenic having the imaginable to germinate into a backbone therapy for the attraction of aggregate myeloma.
In Q3 2025, the company’s pb candidate, cemsidomide, showed a imaginable best-in-class illustration successful Phase 1 information for aggregate myeloma. At the highest dose level of 100 µg, the therapy achieved a 53% wide effect rate. The results indicated a differentiated information and tolerability illustration adjacent successful a heavy pre-treated diligent population. To grow the drug’s reach, C4T entered a objective proceedings collaboration and proviso statement with Pfizer to measure cemsidomide successful operation with elranatamab.
Looking up to 2026, C4T is connected way to initiate the adjacent signifier of improvement for cemsidomide. C4 Therapeutics Inc. (NASDAQ:CCCC) plans to motorboat the Phase 2 MOMENTUM proceedings successful operation with dexamethasone successful Q1 2026, which holds imaginable for accelerated approval. Following this, a Phase 1b proceedings successful operation with Pfizer’s elranatamab is scheduled to statesman successful Q2 2026. These trials purpose to solidify cemsidomide’s presumption successful the relapsed/refractory aggregate myeloma attraction landscape. Beyond oncology, C4T is leveraging its TORPEDO level to advancement a find pipeline targeting non-oncology indications.
C4 Therapeutics Inc. (NASDAQ:CCCC) is simply a clinical-stage biopharmaceutical institution that develops caller therapeutic candidates to degrade disease-causing proteins.
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Disclosure: None. This nonfiction is primitively published at Insider Monkey.

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